Vasopressin Regulates Extracellular Vesicle Uptake by Kidney Collecting Duct Cells.

@article{Oosthuyzen2016VasopressinRE,
  title={Vasopressin Regulates Extracellular Vesicle Uptake by Kidney Collecting Duct Cells.},
  author={Wilna Oosthuyzen and Kathleen Maria Scullion and Jessica R. Ivy and Emma E. Morrison and Robert W. Hunter and Philip J. Starkey Lewis and Eoghan O'Duibhir and Jonathan M. Street and Andrea Caporali and Christopher D Gregory and Stuart J Forbes and David J. Webb and Matthew A Bailey and J W Dear},
  journal={Journal of the American Society of Nephrology : JASN},
  year={2016},
  volume={27 11},
  pages={3345-3355}
}
Extracellular vesicles (ECVs) facilitate intercellular communication along the nephron, with the potential to change the function of the recipient cell. However, it is not known whether this is a regulated process analogous to other signaling systems. We investigated the potential hormonal regulation of ECV transfer and report that desmopressin, a vasopressin analogue, stimulated the uptake of fluorescently loaded ECVs into a kidney collecting duct cell line (mCCDC11) and into primary cells… CONTINUE READING
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