Vasomotor instability preceding tilt-induced syncope: does respiration play a role?

@article{Lipsitz1997VasomotorIP,
  title={Vasomotor instability preceding tilt-induced syncope: does respiration play a role?},
  author={Lewis A. Lipsitz and Raymond J. Morin and Margaret M Gagnon and Dan K. Kiely and A Medina},
  journal={Journal of applied physiology},
  year={1997},
  volume={83 2},
  pages={
          383-90
        }
}
This study aimed to determine whether alterations in cardiovascular dynamics before syncope are related to changes in spontaneous respiration. Fifty-two healthy subjects underwent continuous heart rate (HR), arterial blood pressure (BP), and respiratory measurements during 10-min periods of spontaneous and paced breathing (0.25 Hz) in the supine and 60 degrees head-up tilt positions. Data were evaluated by power spectrum and transfer function analyses. During tilt, 27 subjects developed syncope… 
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31 Citations
Background Citations
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Methods Citations
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Results Citations
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31 Citations

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Citation Type

Complex demodulation of cardiorespiratory dynamics preceding vasovagal syncope.
Orthostatic stress causes immediately increased blood pressure variability in women with vasovagal syncope
Impaired arterial baroreflex function before nitrate-induced vasovagal syncope during head-up tilt test.
TLDR
A significant depression in BRS and BEI occurs immediately before syncope in patients who faint after nitrate administration, thus suggesting that arterial baroreflex dysfunction plays a role in mediating nitrate-induced VVS.
Complex demodulation of cardiorespiratory dynamics preceding vasovagal syncope.
TLDR
Vasovagal syncope is preceded by a period of hyperpnea and cardiorespiratory decoupling followed by an abrupt increase in cardiovagal tone, which may partially counteract preload reduction until sudden bradycardia precipitates syncope.
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Shortened Head-Up Tilting Test Guided by Systolic Pressure Reductions in Neurocardiogenic Syncope
TLDR
In healthy subjects with unexplained syncope, the evaluation of SAP reductions during the first 15 minutes of tilt is a marker of systolic pressure instability preceding syncope and constitutes a simple and good predictor of tilt outcome that could be used to guide test duration.
Independent role of reduced arterial baroreflex sensitivity during head-up tilt testing in predicting vasovagal syncope recurrence.
  • M. Iacoviello, C. Forleo, +5 authors S. Favale
  • Medicine, Biology
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
  • 2010
TLDR
Reducing arterial baroreflex sensitivity during head-up tilt testing has independent and incremental value in predicting the recurrence of syncope, thus supporting its potential usefulness in the clinical management of patients.
Respiration drives phase synchronization between blood pressure and RR interval following loss of cardiovagal baroreflex during vasovagal syncope.
TLDR
Loss of the cardiovagal baroreflex, thoracic hypovolemia, and hyperpnea contribute to the nonlinear time-dependent hemodynamic instability of vasovagal syncope and phase differences directly are examined.
Intravenous cannulation of adolescents does not affect the modulation of autonomic tone assessed by heart rate and blood pressure variability
TLDR
Data suggest, at most, a limited effect of IV insertion on autonomic function in adolescents, and blood pressure andBlood pressure variability were not different, but no parameter changed after IV insertion.
Intravenous cannulation of adolescents does not affect the modulation of autonomic tone assessed by heart rate and blood pressure variability
  • J. Stewart
  • Medicine
    Clinical autonomic research : official journal of the Clinical Autonomic Research Society
  • 2000
TLDR
Data suggest, at most, a limited effect of IV insertion on autonomic function in adolescents, and blood pressure andBlood pressure variability were not different, but no parameter changed after IV insertion.
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