Vasomotor effects of noradrenaline, acetylcholine, histamine, 5-hydroxytryptamine and bradykinin on snake (Trimeresurus flavoviridis) basilar arteries.

@article{Yoshinaga2007VasomotorEO,
  title={Vasomotor effects of noradrenaline, acetylcholine, histamine, 5-hydroxytryptamine and bradykinin on snake (Trimeresurus flavoviridis) basilar arteries.},
  author={Narihiro Yoshinaga and Tadatune Okuno and Yutaka X. Watanabe and Tsukasa Matsumoto and Mitsuya Shiraishi and Takeshi Obi and Akira Yabuki and Atsushi Miyamoto},
  journal={Comparative biochemistry and physiology. Toxicology & pharmacology : CBP},
  year={2007},
  volume={146 4},
  pages={
          478-83
        }
}
We investigated the responsiveness of basilar arterial rings isolated from snakes to noradrenaline (NA), acetylcholine (ACh), histamine (His), 5-hydroxytryptamine (5-HT), mammalian bradykinin (BK) and rattlesnake BK. We also examined whether endothelial cells were involved in the responsiveness to ACh, BK, rattlesnake BK and in their resting vascular tone. NA and 5-HT induced concentration-dependent contractions. The cumulative concentration response curves of NA and 5-HT were shifted to the… CONTINUE READING