Vasomotor Rhinitis: Clinical Efficacy of Azelastine Nasal Spray in Comparison with Placebo

  title={Vasomotor Rhinitis: Clinical Efficacy of Azelastine Nasal Spray in Comparison with Placebo},
  author={P. G{\'e}hanno and E. Deschamps and E. Garay and M. Baehre and R. Garay},
  pages={76 - 81}
  • P. Géhanno, E. Deschamps, +2 authors R. Garay
  • Published 2001
  • Medicine
  • ORL
  • The H1 antagonist azelastine is used in nasal sprays for the treatment of allergic rhinitis, but its therapeutic efficacy in vasomotor rhinitis is unknown. We performed a multicenter randomized double-blind placebo-controlled study of the efficacy and tolerance of azelastine nasal spray in 89 adult patients with vasomotor rhinitis (confirmed by negative Phadiatop). Following a washout period, patients were treated for 15 days with one puff three times daily per nostril of azelastine (n = 44) or… CONTINUE READING
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