Vasohibin 2 promotes human luminal breast cancer angiogenesis in a non-paracrine manner via transcriptional activation of fibroblast growth factor 2.

@article{Tu2016Vasohibin2P,
  title={Vasohibin 2 promotes human luminal breast cancer angiogenesis in a non-paracrine manner via transcriptional activation of fibroblast growth factor 2.},
  author={Min Tu and Cheng Lu and Nan Lv and Jishu Wei and Zipeng Lu and Chunhua Xi and Jianmin Chen and Feng Guo and Kuirong Jiang and Qiang Li and Junli Wu and Guoxin Song and Shui Wang and Wentao Gao and Yi Miao},
  journal={Cancer letters},
  year={2016},
  volume={383 2},
  pages={272-281}
}
Vasohibin 2 (VASH2) is an angiogenic factor and cancer-related protein that acts via paracrine mechanisms. Here, we investigated the angiogenic function and mechanism of action of VASH2 in 200 human breast cancer tissues by performing immunohistochemical staining, western blot, indirect sandwich enzyme-linked immunosorbent assay (ELISA), and a semi-quantitative sandwich-based antibody array. Breast cancer cells stably overexpressing VASH2 or with knocked-down VASH2 were established and used for… CONTINUE READING