Vasodilatory effects of B-type natriuretic peptide are impaired in patients with chronic heart failure.

@article{Nakamura1998VasodilatoryEO,
  title={Vasodilatory effects of B-type natriuretic peptide are impaired in patients with chronic heart failure.},
  author={Mari Nakamura and N. Arakawa and Hiroaki Yoshida and Shigeru Makita and Hiroyuki Niinuma and Katsuhiko Hiramori},
  journal={American heart journal},
  year={1998},
  volume={135 3},
  pages={414-20}
}
BACKGROUND B-type natriuretic peptide (BNP) and atrial natriuretic peptide (ANP) are secreted from the heart and are thought to be equally important factors in the regulation of vascular tone in health and in congestive heart failure (CHF). However, no studies directly compare vasodilator effects of these peptides in healthy subjects and in patients with CHF. METHODS Plethysmography was used to determine the vasodilatory effects of BNP and to compare these to the effects of ANP in patients… CONTINUE READING