Vasodilator effects of quercetin in isolated rat vascular smooth muscle.

@article{Duarte1993VasodilatorEO,
  title={Vasodilator effects of quercetin in isolated rat vascular smooth muscle.},
  author={Juan Duarte and Francisco Perez-Vizcaino and Antonio Zarzuelo and J. R. Perez Jimenez and Juan Tamargo},
  journal={European journal of pharmacology},
  year={1993},
  volume={239 1-3},
  pages={
          1-7
        }
}
Possible Involvement of Ca Activated K Channels, SK Channel, in the Quercetin-Induced Vasodilatation.
  • Seiichiro Nishida, H. Satoh
  • Biology, Medicine
    The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology
  • 2009
TLDR
Among the mechanisms for quercetin-induced vasodilatation in rat aorta, the involvement with the Ca(2+) activated K(+) (K(Ca) channel was examined, with results indicating that quercETin contributes to the vasodILatation selectively with SK channel on smooth muscle.
Involvement of thromboxane A2 in the endothelium‐dependent contractions induced by myricetin in rat isolated aorta
TLDR
The results suggests that myricetin stimulates Ca2+ influx and subsequently triggers the activation of the PLA2 and cyclo‐oxygenase pathways releasing TXA2 from the endothelium to contract rat aortic rings.
Effect of Quercetin and Rutin on Concentration-Response Curves to Isoprenaline and Sodium Nitroprusside
TLDR
The results suggest that the bronchodilator effects of quercetin are modulated by an increase in cyclic nucleotide levels as well as an alteration in availability of Ca to the contractile machinery.
Cardio-Electopharmacology and Vasodilating Mechanisms of Quercetin
TLDR
In rat aorta, quercetin relaxed the contraction induced by pretreatment with 5 μM norepinephrine (NE) in aconcentration-dependent manner and dilates the vascular smooth muscle mediated by endothelium-dependent and -independent mechanisms.
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TLDR
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TLDR
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