Vasodilative response to hypoxia and simulated ischemia is mediated by ATP-sensitive K+ channels in guinea pig thoracic aorta.

@article{Gasser1993VasodilativeRT,
  title={Vasodilative response to hypoxia and simulated ischemia is mediated by ATP-sensitive K+ channels in guinea pig thoracic aorta.},
  author={Roland Gasser and Werner Klein and E Kickenweiz},
  journal={Angiology},
  year={1993},
  volume={44 3},
  pages={228-43}
}
Local vasodilation in response to hypoxia or ischemia improves perfusion and O2 supply of the affected tissue. This local vasodilation thus constitutes the most important mechanism in the prevention of ischemic cell injury. The regulation of vascular tone has mainly been attributed to changes of cytoplasmatic Ca2+ ((Ca2+)i) concentrations in vascular smooth… CONTINUE READING