Vasodilation to PTH (1-84) in bone arteries is dependent upon the vascular endothelium and is mediated partially via VEGF signaling.

@article{Prisby2013VasodilationTP,
  title={Vasodilation to PTH (1-84) in bone arteries is dependent upon the vascular endothelium and is mediated partially via VEGF signaling.},
  author={Rhonda D. Prisby and Thomas Menezes and Jeremiah Cedric Campbell},
  journal={Bone},
  year={2013},
  volume={54 1},
  pages={68-75}
}
BACKGROUND Intermittent PTH administration directly stimulates osteoblasts; however, mechanisms of bone accrual that are independent of the direct actions on osteoblasts may be under-appreciated. Our aims were to decipher (1) whether PTH 1-84 augments vasodilation of the femoral principal nutrient artery (PNA), (2) whether 15 days of intermittent PTH 1-84 augments endothelium-dependent and/or -independent vasodilation of the femoral PNA, and (3) the signaling mechanisms involved. METHODS… CONTINUE READING
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