Vasodilating effects of tetrazepam in isolated vascular smooth muscles: comparison with cromakalim and diltiazem.

Abstract

The vasodilating effects of tetrazepam (1,4-benzodiazepine derivative) were studied and compared with those of the K-channel activator, cromakalim and the Ca-channel blocker, diltiazem, in rat aorta smooth muscle and on the spontaneous contractile activity of the rat portal vein. In the aorta, tetrazepam (3 x 10(-7)-10(-4) M) and diltiazem (10(-8)-3 x 10(-6… (More)

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@article{PrezGuerrero1997VasodilatingEO, title={Vasodilating effects of tetrazepam in isolated vascular smooth muscles: comparison with cromakalim and diltiazem.}, author={C. N. P{\'e}rez-Guerrero and Juan Evaristo Su{\'a}rez and Mar{\'i}a Dolores Herrera and Elisa Marhuenda}, journal={Pharmacological research}, year={1997}, volume={36 3}, pages={237-42} }