Vasoconstriction and anti-inflammatory properties of the selective α-adrenergic receptor agonist brimonidine.

@article{Piwnica2014VasoconstrictionAA,
  title={Vasoconstriction and anti-inflammatory properties of the selective $\alpha$-adrenergic receptor agonist brimonidine.},
  author={David Piwnica and Carine Rosignoli and S{\'e}verine Thibaut de M{\'e}nonville and Thierry Alvarez and Marlene Schuppli Nollet and Olivier Roye and Andr{\'e} Jomard and Jerome Aubert},
  journal={Journal of dermatological science},
  year={2014},
  volume={75 1},
  pages={
          49-54
        }
}
BACKGROUND The facial erythema of rosacea is recognized as the most prevalent and most difficult manifestation of rosacea to treat. [...] Key Method The vasoconstrictive effects of brimonidine were measured using ex vivo wire myography and human skin biopsy neuroinflammation models. The anti-inflammatory properties of brimonidine were measured using two in vivo mice ear inflammation models. Expand

Paper Mentions

Interventional Clinical Trial
The aim of the study is to investigate whether brimonidine cream can reduce IPL-induced inflammation in terms of redness, swelling and pain in patients with facial vascular lesions… Expand
ConditionsTelangiectasias
InterventionDrug, Other
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