Vasoactive properties of dihomo-gamma-linolenic acid and series one prostaglandins in a freshwater teleost, Channa maculata.

@article{Woo1989VasoactivePO,
  title={Vasoactive properties of dihomo-gamma-linolenic acid and series one prostaglandins in a freshwater teleost, Channa maculata.},
  author={Norman Y. S. Woo and E. L. P. Chan and Ka Lung Yu},
  journal={Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology},
  year={1989},
  volume={92 1},
  pages={95-101}
}
1. Prostaglandins A1, B1, E1 and F1 alpha (2-120 micrograms/kg), arachidonic acid and dihomo-gamma-linolenic acid (0.1-2 mg/kg) were injected intravenously into Channa maculata and changes in arterial blood pressure were recorded. 2. Injection of PGF1 alpha had no significant effect on arterial blood pressure. Injection of PGA1 and PGE1 was followed by dose-dependent hypotension whereas injection of PGB1 elicited significant dose-dependent increase in arterial blood pressure. 3. Both dihomo… CONTINUE READING