Vasoactive properties of CORM‐3, a novel water‐soluble carbon monoxide‐releasing molecule

@article{Foresti2004VasoactivePO,
  title={Vasoactive properties of CORM‐3, a novel water‐soluble carbon monoxide‐releasing molecule},
  author={Roberta Foresti and Jehad Hammad and James E. Clark and Tony R Johnson and Brian E. Mann and Andreas Friebe and Colin J. Green and Roberto Motterlini},
  journal={British Journal of Pharmacology},
  year={2004},
  volume={142}
}
Carbon monoxide (CO), one of the end products of heme catabolism by heme oxygenase, possesses antihypertensive and vasodilatory characteristics. We have recently discovered that certain transition metal carbonyls are capable of releasing CO in biological fluids and modulate physiological functions via the delivery of CO. Because the initial compounds identified were not water soluble, we have synthesized new CO‐releasing molecules that are chemically modified to allow solubility in water. The… Expand
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  • FASEB journal : official publication of the Federation of American Societies for Experimental Biology
  • 2005
TLDR
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  • British journal of pharmacology
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TLDR
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TLDR
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TLDR
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TLDR
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