Vasoactive intestinal peptide stimulates ACTH and corticosterone release after injection into the PVN.

@article{Alexander1994VasoactiveIP,
  title={Vasoactive intestinal peptide stimulates ACTH and corticosterone release after injection into the PVN.},
  author={Lerner Alexander and Linda D. Sander},
  journal={Regulatory peptides},
  year={1994},
  volume={51 3},
  pages={221-7}
}
Vasoactive intestinal peptide (VIP), a neuropeptide originally isolated from the intestine, is widely distributed in the central and peripheral nervous systems and exhibits a broad range of biological actions. In the present study the effects of VIP on plasma ACTH and corticosterone (CORT) secretion were investigated in fasted, freely-moving male rats. Male rats, chronically implanted with a hypothalamic paraventricular nucleus (PVN) cannula, were injected with VIP doses (0.15-3.0 nmol/rat) of… CONTINUE READING