Vasoactive intestinal peptide in the brain of a mouse model for Down syndrome.

@article{Hill2003VasoactiveIP,
  title={Vasoactive intestinal peptide in the brain of a mouse model for Down syndrome.},
  author={Joanna M. Hill and Anne M. Ades and S K Mccune and Nadia Sahir and Elizabeth M Moody and Daniel T Abebe and Linda S. Crnic and Douglas E. Brenneman},
  journal={Experimental neurology},
  year={2003},
  volume={183 1},
  pages={56-65}
}
The most common genetic cause of mental retardation is Down syndrome, trisomy of chromosome 21, which is accompanied by small stature, developmental delays, and mental retardation. In the Ts65Dn segmental trisomy mouse model of Down syndrome, the section of mouse chromosome 16 most homologous to human chromosome 21 is trisomic. This model exhibits aspects of Down syndrome including growth restriction, delay in achieving developmental milestones, and cognitive dysfunction. Recent data link… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

Similar Papers

Loading similar papers…