Vasculotide reduces pulmonary hyperpermeability in experimental pneumococcal pneumonia

Abstract

BACKGROUND Community-acquired pneumonia (CAP) is a significant cause of morbidity and mortality worldwide. Despite effective antimicrobial therapy, CAP can induce pulmonary endothelial hyperpermeability resulting in life-threatening lung failure due to an exaggerated host-pathogen interaction. Treatment of acute lung injury is mainly supportive because key… (More)
DOI: 10.1186/s13054-017-1851-6

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