Vasculogenesis and Angiogenesis as Mechanisms of Vascular Network Formation, Growth and Remodeling

@article{Patan2000VasculogenesisAA,
  title={Vasculogenesis and Angiogenesis as Mechanisms of Vascular Network Formation, Growth and Remodeling},
  author={Sybill Patan},
  journal={Journal of Neuro-Oncology},
  year={2000},
  volume={50},
  pages={1-15}
}
Two distinct mechanisms, vasculogenesis and angiogenesis implement the formation of the vascular network in the embryo. Vasculogenesis gives rise to the heart and the first primitive vascular plexus inside the embryo and in its surrounding membranes, as the yolk sac circulation. Angiogenesis is responsible for the remodeling and expansion of this network. While vasculogenesis refers to in situ differentiation and growth of blood vessels from mesodermal derived hemangioblasts, angiogenesis… CONTINUE READING
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