Vascularized limb transplantation in the rat. I. Results with syngeneic grafts.


A microsurgical model was developed to study the transplantation of large sections of vascularized skeletal tissue in inbred rats. A modified vascularized leg graft, consisting of the distal femur, knee joint, and intact tibia, with the associated musculature, was orthotopically transplanted in Fischer F344 rats. The femoral artery and vein were anastomosed… (More)


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