Vascularization pattern of c6 glioma is modified with medroxyprogesterone acetate and ibuprofen in Wistar rat brain

Abstract

Beneficial effects of medroxyprogesterone acetate (MPA) in cancer therapy is partly mediated via its antiangiogenic activity. The same is true for the antitumoral action of non-steroidal antiinflammatory drugs. We have studied two liposoluble drugs, MPA and the analgesic ibuprofen, on glioma vascularizationin vivo. In this study we have shown that, until… (More)
DOI: 10.1007/BF03032347

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