Vascularization of cutaneous melanoma involves vessel co-option and has clinical significance.

@article{Dme2002VascularizationOC,
  title={Vascularization of cutaneous melanoma involves vessel co-option and has clinical significance.},
  author={Bal{\'a}zs D{\"o}me and S{\'a}ndor Paku and Be{\'a}ta Somlai and J{\'o}zsef T{\'i}m{\'a}r},
  journal={The Journal of pathology},
  year={2002},
  volume={197 3},
  pages={
          355-62
        }
}
This study was undertaken to determine the role and the fate of the peritumoural vascular plexus during the vascularization of human malignant melanoma (hMM) and in an appropriate murine melanoma model system. The prognostic significance of the vascularity of different tumour areas was also evaluated. Despite morphometry revealing several-fold higher microvessel densities (MVDs) in the peritumoural tissue than at the centre of the tumour, the development of visceral metastases of hMM was… CONTINUE READING

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