Vascularisation of the central nervous system

@inproceedings{Tata2015VascularisationOT,
  title={Vascularisation of the central nervous system},
  author={Mathew Tata and Christiana Ruhrberg and Alessandro Valter Fantin},
  booktitle={Mechanisms of Development},
  year={2015}
}
The developing central nervous system (CNS) is vascularised through the angiogenic invasion of blood vessels from a perineural vascular plexus, followed by continued sprouting and remodelling until a hierarchical vascular network is formed. Remarkably, vascularisation occurs without perturbing the intricate architecture of the neurogenic niches or the emerging neural networks. We discuss the mouse hindbrain, forebrain and retina as widely used models to study developmental angiogenesis in the… CONTINUE READING
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