Vascular tumor growth and treatment: consequences of polyclonality, competition and dynamic vascular support.

@article{Jackson2002VascularTG,
  title={Vascular tumor growth and treatment: consequences of polyclonality, competition and dynamic vascular support.},
  author={Trachette L. Jackson},
  journal={Journal of mathematical biology},
  year={2002},
  volume={44 3},
  pages={201-26}
}
A mathematical model is presented to describe the evolution of a vascular tumor in response to traditional chemotherapeutic treatment. Particular attention is paid to the effects of a dynamic vascular support system in a tumor comprised of competing cell populations that differ in proliferation rates and drug susceptibility. The model consists of a system of partial differential equations governing intratumoral drug concentration, cancer cell density, and blood vessel density. The balance… CONTINUE READING

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