Vascular smooth muscle phenotypic diversity and function.

  title={Vascular smooth muscle phenotypic diversity and function.},
  author={Steven Fisher},
  journal={Physiological genomics},
  volume={42A 3},
The control of force production in vascular smooth muscle is critical to the normal regulation of blood flow and pressure, and altered regulation is common to diseases such as hypertension, heart failure, and ischemia. A great deal has been learned about imbalances in vasoconstrictor and vasodilator signals, e.g., angiotensin, endothelin, norepinephrine, and nitric oxide, that regulate vascular tone in normal and disease contexts. In contrast there has been limited study of how the phenotypic… CONTINUE READING