Vascular risk factors are associated with faster decline of Alzheimer disease: a longitudinal SPECT study

Abstract

We investigated the effects of cardiovascular risk factors, such as hypertension, diabetes mellitus, and hypercholesterolemia, on longitudinal regional cerebral blood flow (rCBF) changes in Alzheimer’s disease (AD). We followed 68 outpatients with probable AD for an average of 40 months. They were divided into three groups based on no (n = 24), single (n… (More)
DOI: 10.1007/s00415-011-5927-y

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