Vascular responses to drug eluting stents: importance of delayed healing.

  title={Vascular responses to drug eluting stents: importance of delayed healing.},
  author={Aloke Virmani Finn and Gaku Nakazawa and Michael D. Joner and Frank D Kolodgie and E. Mont and Herman Kalman Gold and Renu Virmani},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  volume={27 7},
Polymer-based sirolimus- (Cypher) and paclitaxel-eluting (Taxus) drug eluting stents have become the treatment of choice for patients with symptomatic coronary artery disease undergoing percutaneous coronary intervention (PCI). Although these stents reduce rates of restenosis compared with bare metal stents (BMS), late thrombosis, a life threatening complication, has emerged as a major safety concern. Our understanding of the pathophysiology of late DES thrombosis is derived from animal and… CONTINUE READING
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