Vascular progenitor cells isolated from human embryonic stem cells give rise to endothelial and smooth muscle like cells and form vascular networks in vivo.

@article{Ferreira2007VascularPC,
  title={Vascular progenitor cells isolated from human embryonic stem cells give rise to endothelial and smooth muscle like cells and form vascular networks in vivo.},
  author={Lino Ferreira and Sharon Gerecht and Hester F Shieh and Nicki Watson and Maria A Rupnick and Susan M. Dallabrida and Gordana Vunjak-Novakovic and Robert Langer},
  journal={Circulation research},
  year={2007},
  volume={101 3},
  pages={286-94}
}
We report that human embryonic stem cells contain a population of vascular progenitor cells that have the ability to differentiate into endothelial-like and smooth muscle (SM)-like cells. Vascular progenitor cells were isolated from EBs grown in suspension for 10 days and were characterized by expression of the endothelial/hematopoietic marker CD34 (CD34+ cells). When these cells are subsequently cultured in EGM-2 (endothelial growth medium) supplemented with vascular endothelial growth factor… CONTINUE READING

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