Vascular permeability factor gene expression in normal and neoplastic human ovaries.

@article{Olson1994VascularPF,
  title={Vascular permeability factor gene expression in normal and neoplastic human ovaries.},
  author={Tod A. Olson and Dheepak Mohanraj and Linda F. Carson and Sundaram Ramakrishnan},
  journal={Cancer research},
  year={1994},
  volume={54 1},
  pages={
          276-80
        }
}
Epithelial ovarian cancer is an aggressive malignancy with a generally poor outcome. To improve survival, novel therapeutic strategies for this disease are needed and require elucidation of the biological events that underlie transformation and tumor growth. Vascular permeability factor (VPF), also known as vascular endothelial growth factor, is a homodimeric glycoprotein that acts on vascular endothelium as a potent permeability-inducing agent and mitogen. The present study demonstrates for… CONTINUE READING

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