Vascular permeability enhancement in solid tumor: various factors, mechanisms involved and its implications.

@article{Maeda2003VascularPE,
  title={Vascular permeability enhancement in solid tumor: various factors, mechanisms involved and its implications.},
  author={Hiroshi Maeda and Jun Fang and Takao Inutsuka and Yasunori Kitamoto},
  journal={International immunopharmacology},
  year={2003},
  volume={3 3},
  pages={
          319-28
        }
}
Most solid tumors are known to exhibit highly enhanced vascular permeability, similar to or more than the inflammatory tissues. Common denominators affecting both cancer and inflammatory lesions are now well known: bradykinin (BK), nitric oxide (NO), peroxynitrite (ONOO(-)), prostaglandins (PGs), collagenases or matrix metalloproteinases (MMPs) and others. Incidentally, enzymes involved in these mediator syntheses are upregulated or activated. Initially described vascular permeability factor… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 213 CITATIONS, ESTIMATED 64% COVERAGE

Roadmap to Clinical Use of Gold Nanoparticles for Radiation Sensitization.

  • International journal of radiation oncology, biology, physics
  • 2016
VIEW 6 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Sequence dependence of C-end rule peptides in binding and activation of neuropilin-1 receptor.

  • Journal of structural biology
  • 2013
VIEW 6 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Binding of a C-end rule peptide to the neuropilin-1 receptor: a molecular modeling approach.

  • Biochemistry
  • 2011
VIEW 4 EXCERPTS
CITES METHODS & BACKGROUND
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

2004
2019

CITATION STATISTICS

  • 6 Highly Influenced Citations

  • Averaged 12 Citations per year from 2017 through 2019