Vascular pathology of homocysteinemia: implications for the pathogenesis of arteriosclerosis.

  title={Vascular pathology of homocysteinemia: implications for the pathogenesis of arteriosclerosis.},
  author={Kilmer S. McCully},
  journal={The American journal of pathology},
  volume={56 1},
NDiviDuAI with homocystinuria 12 have been found to lack normal activity of the enzyme cystathionine synthetase.3 In many of the patients progressive arterial disease develops in ildhood, frequently resulting in death from thrombosis in a vital organ45 In addition, congenital dislocation of the lenses, mental retardation, and skeletal abnormalitieseg, osteoporosis, arachnodactyly, and pectus excavatum or pectus carinatum-usually are foundL5' The vascular changes and other abnormalities… CONTINUE READING
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