Vascular parkinsonism: what makes it different?

@article{Gupta2011VascularPW,
  title={Vascular parkinsonism: what makes it different?},
  author={D. Gupta and A. Kuruvilla},
  journal={Postgraduate Medical Journal},
  year={2011},
  volume={87},
  pages={829 - 836}
}
Vascular parkinsonism (VP) accounts for 2.5–5% of all cases of parkinsonism in various population based and clinical cohort studies. VP develops as a result of ischaemic cerebrovascular disease, so aetiologically it is classified as secondary parkinsonism. It has been variably referred to in the literature as arteriosclerotic parkinsonism, vascular pseudo-parkinsonism, and lower body parkinsonism. The most important consideration while making a diagnosis of VP should be to differentiate VP from… Expand
Vascular parkinsonism—characteristics, pathogenesis and treatment
TLDR
Current understanding of the clinical characteristics of VP, as well as knowledge gained from neuroimaging and nuclear imaging of the pathological features of VP are summarized, and consideration is given to whether the overlap between VP and Binswanger disease means that these two disorders should be considered as part of the same disease entity. Expand
Vascular Parkinsonism and cognitive impairment: literature review, Brazilian studies and case vignettes
TLDR
Physicians are provided with an insight on the practical issues of VP, a disease potentially confounded with vascular dementia, idiopathic Parkinson's disease, dementia with Lewy bodies and other secondary causes of Parkinsonism. Expand
Efficacy of dopamine agonist treatment in delayed-onset parkinsonism due to midbrain hemorrhage.
TLDR
A case of VP following a midbrain hemorrhage and involving the substantia nigra (SN) is described, with an exceptionally delayed onset and a symptomatic response to dopamine agonist but not levodopa treatment. Expand
Vascular parkinsonism: a case series of 17 patients.
TLDR
This case series provides a profile of VP with predominant lower-limb involvement, freezing of gait and falls, pyramidal signs, executive dysfunction, concomitant vascular dementia, and poor levodopa response. Expand
Jaw tremor: a manifestation of vascular parkinsonism? - a case report
TLDR
This case describes atypical clinical features which could be associated with VP including jaw tremor and stresses the importance of initiating a trial of levodopa as certain patients may respond well to medication. Expand
Clinicoradiological comparison between vascular parkinsonism and Parkinson’s disease
TLDR
VP can be clinically distinguished from PD based on sudden onset of parkinsonism at an older age, characterised by lower body predominance, urinary incontinence, pyramidal signs, postural instability with freezing of gait and falls, and dementia. Expand
Subclinical vascular disease and the risk of parkinsonism: The Rotterdam Study.
TLDR
A consistent pattern of associations between systemic vascular pathology markers with parkinsonism was not found, suggesting that the potential involvement of vascular pathology is not prominent or needs further evaluation in studies with an even larger sample size. Expand
Clinical Application of Brain MRI in the Diagnostic Work-up of Parkinsonism
TLDR
The main purpose of brain MRI is to assess cerebrovascular damage, and to exclude other possible – and sometimes treatable – causes of parkinsonism, such as normal pressure hydrocephalus. Expand
The Relationship of Clinical Treatment to Quality of Life in a Patient with Vascular Parkinsonism : A Case Report from a Pharmacist ’ s Perspective
Vascular Parkinsonism (VP) is different from Parkinson’s disease (PD). The etiology is still unclear, and clinical diagnosis is often difficult. The present study followed up on the medical treatmentExpand
Dramatic improvement by levodopa treatment in a patient with vascular parkinsonism
  • H. Onder
  • Medicine
  • Neurological Sciences
  • 2018
TLDR
The patient was diagnosed as VP in the setting of hypertension-related cerebral small-vessel damage and she was discharged on treatments of 4 × 200/50 mg levodopa/benserazide and 5 mg amlodipine for hypertension. Expand
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