Vascular morphogenesis by adult bone marrow progenitor cells in three-dimensional fibrin matrices.

@article{Rger2008VascularMB,
  title={Vascular morphogenesis by adult bone marrow progenitor cells in three-dimensional fibrin matrices.},
  author={Beate M R{\"u}ger and Johannes M. Breuss and David Hollemann and Genya Yanagida and Michael Bernhard Fischer and Isabella Mosberger and Andreas Chott and Ir{\'e}ne Lang and Paul Frank Davis and Paul Hoecker and Markus Dettke},
  journal={Differentiation; research in biological diversity},
  year={2008},
  volume={76 7},
  pages={772-83}
}
The neovascularization of tissues is accomplished by two distinct processes: de novo formation of blood vessels through the assembly of progenitor cells during early prenatal development (vasculogenesis), and expansion of a pre-existing vascular network by endothelial cell sprouting (angiogenesis), the main mechanism of blood vessel growth in postnatal life. Evidence exists that adult bone marrow (BM)-derived progenitor cells can contribute to the formation of new vessels by their incorporation… CONTINUE READING

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