Vascular healing in drug-eluting stents: differential drug-associated response of limus-eluting stents in a preclinical model of stent implantation.

@article{Steigerwald2012VascularHI,
  title={Vascular healing in drug-eluting stents: differential drug-associated response of limus-eluting stents in a preclinical model of stent implantation.},
  author={Kristin Steigerwald and Simone Ballke and Shawn Chin Quee and Robert A. Byrne and Marc Vorpahl and Michael Vogeser and Frank D Kolodgie and Renu Virmani and Michael D. Joner},
  journal={EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology},
  year={2012},
  volume={8 6},
  pages={752-9}
}
AIMS We aimed to assess the influence of different sirolimus analogues released from a uniform stent platform on re-endothelialisation and vascular healing responses. METHODS AND RESULTS Bare metal stents (BMS) were coated with a fluoropolymer containing everolimus (EES), sirolimus (SES) or zotarolimus (ZES) to generate drug-eluting stents (DES) with identical stent backbones, drug loads and release kinetics. DES constructs and control BMS were implanted into the iliac arteries of rabbits and… CONTINUE READING

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