Vascular expression of extracellular superoxide dismutase in atherosclerosis.

@article{Fukai1998VascularEO,
  title={Vascular expression of extracellular superoxide dismutase in atherosclerosis.},
  author={Tohru Fukai and Zorina S. Galis and Xue Meng and Sumathy Parthasarathy and David G Harrison},
  journal={The Journal of clinical investigation},
  year={1998},
  volume={101 10},
  pages={2101-11}
}
We characterized a novel form of extracellular superoxide dismutase (ecSOD) in atherosclerotic vessels. Specific activity and protein expression of ecSOD was increased two- to threefold in apo E-deficient compared with control aortas. RNase protection assays demonstrated that the expected ecSOD transcript was not increased in either apo E-deficient mice or… CONTINUE READING