Corpus ID: 15096038

Vascular endothelial growth factor upregulates expression of annexin A2 in vitro and in a mouse model of ischemic retinopathy

@article{Zhao2009VascularEG,
  title={Vascular endothelial growth factor upregulates expression of annexin A2 in vitro and in a mouse model of ischemic retinopathy},
  author={Shi-hong Zhao and L. Huang and J. Wu and Y. Zhang and Dongyan Pan and X. Liu},
  journal={Molecular Vision},
  year={2009},
  volume={15},
  pages={1231 - 1242}
}
Purpose Annexin A2 has been shown to play a role in many neovascularization diseases. We investigated the effect of vascular endothelial growth factor (VEGF) on annexin A2 expression and related intracellular signaling mechanisms in a mouse model of ischemia-induced retinal neovascularization. Methods Annexin A2 expression and the effect of vascular endothelial growth factor (VEGF) on annexin A2 ex pression in retinal neovascularization were assayed by real-time PCR, western blot analysis. The… Expand
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