Vascular endothelial growth factor upregulates expression of annexin A2 in vitro and in a mouse model of ischemic retinopathy
@article{Zhao2009VascularEG, title={Vascular endothelial growth factor upregulates expression of annexin A2 in vitro and in a mouse model of ischemic retinopathy}, author={Shi-hong Zhao and L. Huang and J. Wu and Y. Zhang and Dongyan Pan and X. Liu}, journal={Molecular Vision}, year={2009}, volume={15}, pages={1231 - 1242} }
Purpose Annexin A2 has been shown to play a role in many neovascularization diseases. We investigated the effect of vascular endothelial growth factor (VEGF) on annexin A2 expression and related intracellular signaling mechanisms in a mouse model of ischemia-induced retinal neovascularization. Methods Annexin A2 expression and the effect of vascular endothelial growth factor (VEGF) on annexin A2 ex pression in retinal neovascularization were assayed by real-time PCR, western blot analysis. The… Expand
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