Vascular endothelial growth factor stimulates dephosphorylation of the catenins p120 and p100 in endothelial cells.

@article{Wong2000VascularEG,
  title={Vascular endothelial growth factor stimulates dephosphorylation of the catenins p120 and p100 in endothelial cells.},
  author={E Y Wong and Louise Morgan and Caroline Smales and Paul Lang and S E Gubby and James M. Staddon},
  journal={The Biochemical journal},
  year={2000},
  volume={346 Pt 1},
  pages={209-16}
}
Vascular endothelial growth factor (VEGF) is an endothelium-specific mitogen that induces angiogenesis and increases vascular permeability. These processes involve regulation of cell-cell adhesion, but molecular mechanisms have yet to be fully established. p120, also termed p120(ctn), and its variant p100 are catenins which associate with cadherins and localize to adherens junctions. VEGF was reported to stimulate tyrosine phosphorylation of catenins in endothelial cells. In contrast, we have… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

Similar Papers

Loading similar papers…