Vascular endothelial growth factor serum level is strongly enhanced after burn injury and correlated with local and general tissue edema.

@article{Infanger2004VascularEG,
  title={Vascular endothelial growth factor serum level is strongly enhanced after burn injury and correlated with local and general tissue edema.},
  author={Manfred Infanger and Oliver Schmidt and Peter Kossmehl and Sibylle Grad and Wolfgang Ertel and Daniela Grimm},
  journal={Burns : journal of the International Society for Burn Injuries},
  year={2004},
  volume={30 4},
  pages={305-11}
}
BACKGROUND Burn associated local and general tissue edema is induced by local cell destruction and capillary leak syndrome. Vascular endothelial growth factor (VEGF) strongly enhances vascular permeability as well as angiogenesis. The principal aim of this study was to investigate the systemic release of VEGF and its kinetics after severe burn injury in humans. METHODS Thirty-six burn patients and 42 healthy volunteers were enrolled in this study. Circulating VEGF serum levels were measured… CONTINUE READING