Vascular endothelial growth factor is associated with the efficacy of endocrine therapy in patients with advanced breast carcinoma.

@article{Manders2003VascularEG,
  title={Vascular endothelial growth factor is associated with the efficacy of endocrine therapy in patients with advanced breast carcinoma.},
  author={Peggy Manders and Louk V. A. M. Beex and Vivianne C. G. Tjan-Heijnen and Paul N Span and C G J Fred Sweep},
  journal={Cancer},
  year={2003},
  volume={98 10},
  pages={2125-32}
}
BACKGROUND Vascular endothelial growth factor (VEGF) is a mediator of angiogenesis and is associated with a poor prognosis in patients with primary breast carcinoma. In the current study, the authors investigated whether there was an association between VEGF levels in tumor tissues and response rates to first-line, systemic therapy in patients with advanced breast carcinoma. METHODS In 172 tumors from patients with primary breast carcinoma who developed distant metastases during follow-up… CONTINUE READING