Vascular endothelial growth factor expression is higher in differentiated thyroid cancer than in normal or benign thyroid.

@article{Soh1997VascularEG,
  title={Vascular endothelial growth factor expression is higher in differentiated thyroid cancer than in normal or benign thyroid.},
  author={Euy Young Soh and Q. Y. Duh and Sohrab Sobhi and David Matthew Young and Howard D. Epstein and Mariwil G. Wong and Yann Garcia and Young Don Min and Robert Grossman and Allan E. Siperstein and Orlo Herrick Clark},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1997},
  volume={82 11},
  pages={3741-7}
}
Vascular endothelial growth factor (VEGF) is an angiogenic factor, and its expression has been rarely demonstrated in thyroid tumors. We, therefore, investigated the expression of VEGF messenger RNA (mRNA) and production of VEGF protein in cell lines from human primary and metastatic follicular (FTC-133, FTC-236, and FTC-238), papillary (TPC-1), Hürthle cell (XTC-1), and medullary thyroid cancers (MTC-1.1 and MTC-2.2), and in human thyroid tissues (papillary, follicular, medullary, and Hürthle… CONTINUE READING

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