Vascular endothelial growth factor as a therapeutic target in cancer.

@article{Bergsland2004VascularEG,
  title={Vascular endothelial growth factor as a therapeutic target in cancer.},
  author={Emily K Bergsland},
  journal={American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists},
  year={2004},
  volume={61 21 Suppl 5},
  pages={
          S4-11
        }
}
PURPOSE The role of vascular endothelial growth factor (VEGF) in angiogenesis, vascular maintenance, lymphangiogenesis, and immune cell function will be explained. The link between angiogenesis and tumor progression and the rationale for targeting VEGF in the treatment of cancer will be discussed. In addition, the various therapeutic approaches to inhibiting VEGF will be reviewed. SUMMARY Advances in our understanding of the mechanisms underlying tumor progression have translated into a… CONTINUE READING
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