Vascular endothelial growth factor antagonist reduces brain edema formation and venous infarction.

@article{Kimura2005VascularEG,
  title={Vascular endothelial growth factor antagonist reduces brain edema formation and venous infarction.},
  author={Risa Kimura and Hiroyuki Nakase and Ryo Tamaki and Toshisuke Sakaki},
  journal={Stroke},
  year={2005},
  volume={36 6},
  pages={1259-63}
}
BACKGROUND AND PURPOSE Cerebral venous ischemia often induces severe brain edema. Vascular endothelial growth factor (VEGF), which induces angiogenesis, is also known as vascular permeability (VP) factor. The present study was undertaken to investigate whether the inhibition of VEGF could reduce brain edema formation and cerebral venous infarction (CVI) in a rat 2-vein occlusion (2-VO) model. METHODS We used 2-VO model in which 2 adjacent cortical veins were photochemically occluded. Male… CONTINUE READING

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Parenchymal enhancement of Acute Cerebral Venous Infarction in rats

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