Vascular endothelial growth factor-A is a survival factor for nucleus pulposus cells in the intervertebral disc.

Abstract

The intervertebral disc (IVD) is composed of two avascular tissue types, the nucleus pulposus (NP) and the annulus fibrosus (AF). IVDs is the largest avascular tissue in the human body, however, how these tissues are maintained without a blood supply is poorly understood. Here we show that vascular endothelial growth factor-A (VEGF-A) is highly expressed in… (More)
DOI: 10.1016/j.bbrc.2008.05.044

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