Vascular endothelial growth factor (VEGF121) protects rats from renal infarction in thrombotic microangiopathy.

Abstract

BACKGROUND Renal thrombotic microangiopathy, typified by the hemolytic uremic syndrome, is associated with endothelial cell injury in which the presence of cortical necrosis, extensive glomerular involvement, and arterial occlusive lesions correlates with a poor clinical outcome. We hypothesized that the endothelial survival factor vascular endothelial… (More)

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