Vascular endothelial growth factor (VEGF) expression in the subacromial bursa is increased in patients with impingement syndrome

@article{Yanagisawa2001VascularEG,
  title={Vascular endothelial growth factor (VEGF) expression in the subacromial bursa is increased in patients with impingement syndrome},
  author={Kazuhiro Yanagisawa and Kazutoshi Hamada and Masafumi Gotoh and Tetsuji Tokunaga and Yoshiro Oshika and Masashi Tomisawa and Y H Lee and Akiyoshi Handa and Hiroshi Kijima and Hitoshi Yamazaki and M. Nakamura and Yoshito Ueyama and N. Tamaoki and H. Fukuda},
  journal={Journal of Orthopaedic Research},
  year={2001},
  volume={19}
}

Vascular endothelial growth factor 121 and 165 in the subacromial bursa are involved in shoulder joint contracture in type II diabetics with rotator cuff disease

  • A. HandaM. Gotoh H. Fukuda
  • Medicine
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society
  • 2003

Effect of Angiogenesis-Related Cytokines on Rotator Cuff Disease: The Search for Sensitive Biomarkers of Early Tendon Degeneration

TLDR
The pathogenesis of RCD is associated with an imbalance between pro- inflammatory, anti-inflammatory, and vascular ARC, and high blood vessel density in patients with tendon rupture is shown.

The molecular pathophysiology of subacromial bursitis in rotator cuff disease.

Growth factor expression after supraspinatus tear: a quantitative polymerase chain reaction (PCR) study in rats

TLDR
IL-1β was expressed predominantly in the initial stages after injury; TGF initiated its expression after the initial phase since day three, whereas VEGF remained basically unchanged during the entire process.

Biomolecules Related to Rotator Cuff Pain: A Scoping Review

TLDR
Investigation of molecules from tissue samples taken from the subacromial bursa, supraspinatus tendon, glenohumeral joint fluid, and synovium as well as from peripheral blood for correlation to pain level finds IL-1b is directly positively correlated to the degree of pain in patients with RC tendinopathy.

Gene Expression Profile Analysis by cDNA Array in the Subacromial Bursa of Patients with Rotator Cuff Disease

TLDR
This study demonstrated a significant increase in many inflammatory cytokines in the subacromial bursa of patients with rotator cuff disease, which suggests that there is an active inflammatory reaction at the subACromial Bursa in rotators cuff disease.

Expression of bioactive bone morphogenetic proteins in the subacromial bursa of patients with chronic degeneration of the rotator cuff

TLDR
Sufficient information was gathered to explain how ectopic expression of BMP might induce tissue transformation into ectopic bone/cartilage and, therefore, promote structural degeneration of the rotator cuff.

The prevalence of neovascularity in patients clinically diagnosed with rotator cuff tendinopathy

TLDR
It is demonstrated that neovascularity does occur in subjects with a clinical diagnosis of rotator cuff tendinopathy and to a lesser extent in asymptomatic shoulders.

Stromal cell‐derived factor 1 (SDF‐1, CXCL12) is increased in subacromial bursitis and downregulated by steroid and nonsteroidal anti‐inflammatory agents

TLDR
It is proposed that the resident cells in subacromial bursal tissue produce SDF‐1, which can play a role in the inflammatory reponse of bursesal tissue, and that this chemokine can be regulated by steroid (dexamethasone) and nonsteroidal anti‐inflammatory medications (NSAIDs).
...

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