Vascular endothelial growth factor (VEGF) mRNA splice variants are differentially expressed in human blastocysts.

@article{Krssel2001VascularEG,
  title={Vascular endothelial growth factor (VEGF) mRNA splice variants are differentially expressed in human blastocysts.},
  author={J S Kr{\"u}ssel and Barry R. Behr and Amin A. Milki and Jens Hirchenhain and Yan Wen and Peter Bielfeld and M Lake Polan},
  journal={Molecular human reproduction},
  year={2001},
  volume={7 1},
  pages={57-63}
}
The aim of our study was to detect and characterize mRNA expression of VEGF isoforms VEGF(121), VEGF(145), VEGF(165), VEGF(189), and VEGF(206) in human blastocysts. We recently demonstrated VEGF mRNA expression during human preimplantation embryo development, and further information regarding the alternatively spliced mRNAs resulting in freely secreted proteins or proteins bound to cell surface heparan-sulphate proteoglycans is needed to better understand the process of angiogenesis during… CONTINUE READING