Vascular endothelial growth factor (VEGF) in the pathogenesis of psoriasis--a possible target for novel therapies?

@article{Canavese2010VascularEG,
  title={Vascular endothelial growth factor (VEGF) in the pathogenesis of psoriasis--a possible target for novel therapies?},
  author={Miriam Canavese and Fiorella Altruda and Thomas Ruzicka and J{\"u}rgen Schauber},
  journal={Journal of dermatological science},
  year={2010},
  volume={58 3},
  pages={171-6}
}
Angiogenesis is defined as the formation of new capillaries from pre-existing blood vessels. The process of angiogenesis is tightly regulated by a balance between pro- and anti-angiogenic factors. Vascular endothelial growth factor (VEGF) is a pro-angiogenic factor and several anti-VEGF therapies are used in the treatment of diseases that are characterized by abnormal formation of blood vessels such as certain cancers and age-related macular degeneration. In addition, dysregulated angiogenesis… CONTINUE READING

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