Vascular endothelial growth/permeability factor expression in human glioma specimens: correlation with vasogenic brain edema and tumor-associated cysts.

@article{Strugar1995VascularEG,
  title={Vascular endothelial growth/permeability factor expression in human glioma specimens: correlation with vasogenic brain edema and tumor-associated cysts.},
  author={Jadranka Strugar and Gregory R. Criscuolo and Dr. Peter Rothbart and W N Harrington},
  journal={Journal of neurosurgery},
  year={1995},
  volume={83 4},
  pages={682-9}
}
Peritumoral vasogenic brain edema (PVBE) is a common accompaniment of malignant gliomas. It results from microvascular extravasation of plasma fluid and proteins through the interendothelial spaces. Tumor-associated cysts (TACs) are observed more commonly with benign gliomas that are not associated with PVBE. This study investigates the hypothesis that these morphologically distinct epiphenomena of microvascular extravasation are linked by a common pathophysiological mechanism involving… CONTINUE READING
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