Vascular endothelial cadherin expression in lung specimens of patients with sepsis-induced acute respiratory distress syndrome and endothelial cell cultures.

@article{Herwig2013VascularEC,
  title={Vascular endothelial cadherin expression in lung specimens of patients with sepsis-induced acute respiratory distress syndrome and endothelial cell cultures.},
  author={Martina Christina Herwig and Michael Tsokos and Maria Iris Hermanns and C James Kirkpatrick and Annette Margarete M{\"u}ller},
  journal={Pathobiology : journal of immunopathology, molecular and cellular biology},
  year={2013},
  volume={80 5},
  pages={245-51}
}
AIMS Vascular endothelial (VE) cadherin is a cell adhesion molecule localized at endothelial cell (EC) junctions. As a major component of endothelial adherens junctions, its main function is the maintenance and regulation of EC integrity. In the acute respiratory distress syndrome (ARDS), increased vascular permeability is a major mechanism in pulmonary edema and lung dysfunction. In this study, VE-cadherin expression was investigated in ARDS lungs and control tissue as well as in an ARDS cell… CONTINUE READING

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