Vascular endothelial and smooth muscle function relates to body mass index and glucose in obese and nonobese children.

@article{Pea2006VascularEA,
  title={Vascular endothelial and smooth muscle function relates to body mass index and glucose in obese and nonobese children.},
  author={Alexia S Pe{\~n}a and Esko J. Wiltshire and Karen E MacKenzie and Roger J. Gent and Lino Piotto and Craig Hirte and Jennifer J. Couper},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2006},
  volume={91 11},
  pages={4467-71}
}
CONTEXT Endothelial and smooth muscle dysfunction are critical precursors of atherosclerosis. These can be detected in children at risk of cardiovascular disease. OBJECTIVE The objective of this study is to evaluate endothelial and smooth muscle function and their determinants using flow-mediated dilatation (FMD) and glyceryl trinitrate-mediated dilatation (GTN) in obese, nonobese, and type 1 diabetes mellitus (T1DM) children. DESIGN This is a cross-sectional study. SUBJECTS The study… CONTINUE READING

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