Vascular effects of photodynamic therapy in an intraocular retinoblastoma-like tumour.

@article{Horsman1989VascularEO,
  title={Vascular effects of photodynamic therapy in an intraocular retinoblastoma-like tumour.},
  author={Michael Robert Horsman and Jens B Winther},
  journal={Acta oncologica},
  year={1989},
  volume={28 5},
  pages={693-7}
}
Results from experimental tumours suggest that the mechanism of action of photodynamic therapy (PDT) involves both a direct killing of tumour cells, and a secondary effect resulting from vascular damage. We have investigated the possible vascular changes induced by PDT in an intraocular retinoblastoma-like rat tumour model using the 86RbCl extraction procedure. Light irradiation (90 J/cm2; 633 nm; 30 min) of intraocular tumours 24 h after an intraperitoneal injection of 5 mg/kg Photofrin II… CONTINUE READING

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