• Corpus ID: 110268188

Vascular effects of 3-carbomethoxypyridine on rabbit aortic smooth muscle

@inproceedings{Aikpitanyiiduitua2015VascularEO,
  title={Vascular effects of 3-carbomethoxypyridine on rabbit aortic smooth muscle},
  author={R. O. Aikpitanyi-iduitua and Abiodun Falodun and Anthony B. Ebeigbe},
  year={2015}
}
Background : 3-Carbomethoxypyridine (3-CMP) is a methyl nicotinate that has been isolated and characterized from one of the alkaloidal fractions of Pyrenacantha staudtii. No literature is available on its vascular action. The goal of this study was to characterize the mechanism of action of 3-CMP on rabbit aortic smooth muscle. Methods: Isometric contractions of ring segments of rabbit aorta (under an initial load of 2g) suspended in 20ml organ baths containing physiological salt solution (PSS…